ASTM D8375
Standard Test Method for Determination of Cannabinoid Concentration in Dried Cannabis and Hemp Raw Materials using Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
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- Language: English
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About This Item
ASTM D8375 is a laboratory test method for determining cannabinoid concentration in dried cannabis and hemp raw materials using liquid chromatography tandem mass spectrometry (LC-MS/MS). It provides a focused technical approach for measuring cannabinoid content in dried plant materials, supporting consistent analytical results and better comparison across testing programs. For organizations working with cannabis or hemp raw materials, this standard can help improve quality control, reporting consistency, and confidence in cannabinoid measurement.
Overview of ASTM D8375
The ASTM D8375 standard addresses a specific analytical need: quantifying cannabinoid concentration in dried cannabis and hemp raw materials by LC-MS/MS. As a test method, it is intended to guide laboratory determination of target compounds in a controlled, instrument-based workflow. The title indicates a focus on dried raw materials rather than finished products, making the document relevant to material testing and analytical verification. ASTM D8375 is therefore a practical reference for labs seeking a standardized way to measure cannabinoid levels with mass spectrometric analysis.
Common use cases of ASTM D8375
ASTM D8375 is commonly used in laboratory settings that analyze dried cannabis and hemp raw materials for cannabinoid concentration. It may support incoming material evaluation, routine quality control, product characterization, and verification of analytical results generated by LC-MS/MS systems. The standard is especially useful where consistent measurement of cannabinoids is needed for reporting, internal specification checks, or procurement decisions. In practice, it helps labs align testing workflows around a recognized ASTM standard.
Benefits of using ASTM D8375
Using ASTM D8375 can improve consistency in cannabinoid testing by providing a clear, standardized method for LC-MS/MS analysis. That can support better comparability between laboratories, stronger quality control, and more reliable data for compliance or internal review. It may also reduce ambiguity in testing procedures for dried cannabis and hemp raw materials, helping technical teams evaluate results with greater confidence. For buyers and labs alike, ASTM D8375 offers a useful benchmark for method-based procurement and performance expectations.
- LC-MS/MS-based cannabinoid measurement
- Dried cannabis and hemp raw materials
- Analytical method for lab testing
- Quality control and result consistency
- Standardized technical reference
- Publication Date: 2023-07-10
- Publisher: ASTM
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