ASTM D8456
Standard Test Method for Determination of Nitrosamines in Water by Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
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About This Item
ASTM D8456 is a technical standard for determining nitrosamines in water using liquid chromatography tandem mass spectrometry (LC-MS/MS). It provides a structured analytical approach for laboratories that need reliable identification and measurement of these compounds in water samples. By defining a consistent test method, ASTM D8456 supports clearer comparison of results, stronger quality control, and more dependable decision-making in water testing workflows.
Purpose of ASTM D8456
The purpose of ASTM D8456 is to outline a standardized method for analyzing nitrosamines in water with LC-MS/MS. This matters because the technique is designed to measure target compounds with analytical precision and reproducibility under controlled laboratory conditions. As an ASTM standard, it helps align testing practices around a common technical framework, supporting consistent sample analysis, method validation, and data interpretation for users who need dependable water-quality measurements.
Common use cases of ASTM D8456
This standard is commonly used in laboratory settings where water samples must be screened or measured for nitrosamines. It may apply in environmental testing, water quality evaluation, and analytical workflows that rely on LC-MS/MS instrumentation. ASTM D8456 is especially relevant when laboratories need a defensible test method for routine monitoring, confirmatory analysis, or comparison of results across different facilities and instruments.
Why ASTM D8456 matters
ASTM D8456 matters because standardized test methods help reduce variation in analytical results and improve confidence in reported data. For organizations involved in water testing, it supports compliance efforts, internal quality control, and more consistent procurement or contract specifications. Using a recognized ASTM standard can also help laboratories communicate results clearly and reduce risk when evaluating water samples for nitrosamines.
- LC-MS/MS-based water analysis
- Targeted nitrosamine determination
- Laboratory consistency and repeatability
- Quality control and result comparability
- Technical reference for water testing programs
- Publication Date: 2022-07-08
- Publisher: ASTM
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