ASTM E1242
Standard Practice for Using Octanol-Water Partition Coefficient to Estimate Median Lethal Concentrations for Fish Due to Narcosis
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About This Item
ASTM E1242 is a technical standard that describes how to use the octanol-water partition coefficient to estimate median lethal concentrations for fish due to narcosis. It provides a practical way to relate a substance’s partitioning behavior to aquatic toxicity estimates, supporting screening and comparison when direct test data may not be available. For organizations working with environmental evaluation or chemical assessment, this standard can help improve consistency and decision-making.
Purpose of ASTM E1242
The purpose of ASTM E1242 is to guide the use of octanol-water partition coefficient values as a basis for estimating median lethal concentrations associated with narcosis in fish. This type of practice is typically used to support hazard screening, comparative assessment, and technical review of substances with potential aquatic effects. By linking a measurable physical-chemical property to an estimated biological response, the standard helps users apply a more consistent and documented approach to early-stage evaluation.
Common use cases of ASTM E1242
This standard is commonly used in environmental testing and chemical screening workflows where fish toxicity estimates are needed for review, comparison, or preliminary assessment. ASTM E1242 may be useful in product evaluation, regulatory support, and research settings that rely on partition coefficient data to estimate narcosis-related effects. It is especially relevant when teams need a structured method for interpreting octanol-water partitioning information in relation to aquatic hazard potential.
Why ASTM E1242 matters
ASTM E1242 matters because it supports more consistent and transparent estimation of fish median lethal concentrations using a widely used chemical property. That can improve technical confidence during compliance reviews, procurement checks, and environmental risk screening. For organizations comparing substances or documenting test-based decisions, the standard helps reduce variability in interpretation and provides a recognized framework for estimating likely narcosis-related toxicity from available data.
- Octanol-water partition coefficient based estimation
- Fish median lethal concentration screening
- Narcosis-related aquatic toxicity assessment
- Consistent technical evaluation support
- Useful for comparison and documentation workflows
- Publication Date: 2023-02-15
- Publisher: ASTM
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