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ASTM E2526

Standard Test Method for Evaluation of Cytotoxicity of Nanoparticulate Materials in Porcine Kidney Cells and Human Hepatocarcinoma Cells

Standard by ASTM, 2022-07-21

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ASTM E2526 is a focused ASTM standard for evaluating the cytotoxicity of nanoparticulate materials in porcine kidney cells and human hepatocarcinoma cells. It provides a technical framework for assessing how these materials interact with specific cell models, helping users compare results in a more consistent way. For laboratories and organizations working with nanoparticle evaluation, this standard supports more reliable screening and documentation when biological response is a key concern.

What is ASTM E2526?

This standard, ASTM E2526, outlines a test method centered on cytotoxicity evaluation for nanoparticulate materials using porcine kidney cells and human hepatocarcinoma cells. Based on its title, the document is intended to guide testing conditions and interpretation for cell-based assessment of material effects. It is most useful when a repeatable method is needed to evaluate potential cellular toxicity and to support technical comparison across nanoparticle samples.

Where is ASTM E2526 used?

ASTM E2526 is commonly used in laboratory settings that assess nanoparticulate materials before or during product development, quality review, or research screening. It is relevant where cell-based cytotoxicity data are needed to help characterize material behavior and support internal decision-making. The standard may also be used by testing organizations, materials developers, and compliance-focused teams that need a recognized method for evaluating nanoparticle-related biological response.

Why is ASTM E2526 important?

This standard matters because cytotoxicity results can vary significantly without a defined test method. ASTM E2526 helps improve consistency, comparability, and traceability in nanoparticulate materials evaluation. That can reduce uncertainty during product assessment, support quality control, and make procurement or review decisions easier to defend. For teams handling advanced materials, a clear ASTM standard can also help align testing practices with expected technical and documentation requirements.

  • Nanoparticulate material cytotoxicity testing
  • Porcine kidney cell and human hepatocarcinoma cell models
  • Repeatable laboratory evaluation method
  • Material screening and comparative assessment
  • Technical support for quality and compliance workflows
SKU: 0dc5ece95958

  • Publication Date: 2022-07-21
  • Publisher: ASTM

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